Slay the Spire 2 - Monsters
The enemies and Bosses of Slay the Spire 2, spanning all three Acts and both alternate Act 1 biomes. Each Boss closes out an Act gauntlet, while the many normal and Elite creatures flesh out the overgrown, hive, and mechanized themes of Overgrowth, Underdocks, The Hive, and Glory. Slay the Spire 2 s...
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of 18 entries
· updated 2026-09-15
| Name | Type | Description | Region | Source |
|---|---|---|---|---|
| Ceremonial Beast | Boss | One of the two Bosses that can close the Overgrowth first Act, the Ceremonial Beast is a large, ritual-adorned wild creature. | Act 1 - Overgrowth | Act 1 Overgrowth Boss |
| Kin Priest | Boss | The other Overgrowth closing Boss, the Kin Priest is a shamanic, cult-leaning figure whose fight tests the player's ability to manage supported or summoned threats alongside direct damage. | Act 1 - Overgrowth | Act 1 Overgrowth Boss |
| Lagavulin Matriarch | Boss | The Boss that closes the alternate Underdocks first Act, a towering matriarch variant of the lagoon creature family. | Act 1 - Underdocks | Act 1 Underdocks Boss |
| Queen & Torch Head Amalgam | Boss | A fused Glory Boss pairing the figure of a Queen with a blazing Torch Head, forcing the player to handle escalating fire-construct pressure across the final Act's opening boss slot. | Act 3 - Glory | Act 3 Glory Boss |
| Test Subject | Boss | A Glory Boss themed around a manufactured laboratory construct, challenging decks with scaling health and punishing sustained, grindy fights late in the run. | Act 3 - Glory | Act 3 Glory Boss |
| Door / Doormaker | Boss | A construct Boss that splits into a Door form and a Doormaker builder form, testing the player's ability to deal with a setup-backed defender that gates access to the run's conclusion. | Act 3 - Glory | Act 3 Glory Boss |
| Axebots | Normal Enemy | Mechanized axe-wielding constructs in the Glory third Act, part of the biome's heavy robot presence and straightforward damage threats. | Act 3 - Glory | Act 3 Glory enemy |
| Devoted Sculptor | Normal Enemy | A Glory construct whose sculptor theme frames it as a maker of machines, adding craft-and-summon pressure to Act 3 fights. | Act 3 - Glory | Act 3 Glory enemy |
| Fabricator | Normal Enemy | A production-line construct in Glory that embodies the biome's industrial theme, threatening to assemble additional threats during combat. | Act 3 - Glory | Act 3 Glory enemy |
| Frog Knight | Normal Enemy | A knightly amphibian enemy in the final Act, blending Glory's mechanical tone with a living, armored combatant. | Act 3 - Glory | Act 3 Glory enemy |
| Globe Head | Normal Enemy | A spherical, globe-headed construct in Glory dealing ranged damage pressure, emblematic of the Act's odd-shaped automata. | Act 3 - Glory | Act 3 Glory enemy |
| Living Shield + Turret Operator | Normal Enemy (Pair) | A paired encounter pairing a bulwark-like Living Shield with a Turret Operator that attacks from behind cover, demanding positional focus and multi-target answers. | Act 3 - Glory | Act 3 Glory enemy pair |
| Owl Magistrate | Normal / Elite Enemy | An owl-headed magistrate construct in Glory, a learned, commanding machine whose fight carries debuff and control pressure reminiscent of Neow's feathered kin. | Act 3 - Glory | Act 3 Glory enemy |
| Punch Construct + Cubex | Normal Enemy (Pair) | A paired Glory fight teaming a heavy Punch Construct with a Cubex partner, testing burst damage against a zero-hands-cost offense from the two. | Act 3 - Glory | Act 3 Glory enemy pair |
| Flyconid | Normal Enemy | A flying, fungal-garden creature in the Overgrowth first Act, an early airborne nuisance in the lush opening biome. | Act 1 - Overgrowth | Act 1 Overgrowth enemy |
| Raider Trio | Normal Enemy (Group) | A grouped trio of bandit enemies in Overgrowth, introducing multi-target combat fundamentals in the opening Act. | Act 1 - Overgrowth | Act 1 Overgrowth enemy group |
| Fogmog | Normal Enemy | A mist-veiled creature of the Overgrowth that exemplifies the swampy, obscured corner of the first Act's bestiary. | Act 1 - Overgrowth | Act 1 Overgrowth enemy |
| Mawler | Normal Enemy | A large-mawed beast in the Overgrowth opening Act, a blunt early single-target threat common to the biome's wild-animal lineup. | Act 1 - Overgrowth | Act 1 Overgrowth enemy |
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