Nioh 2 - Bosses
The major boss encounters of Nioh 2, from the opening yokai duels through the human commander duels of the main campaign to the DLC chapters. Each entry covers how the fight works rather than exact damage numbers, because boss stats scale with mission level and New Game Plus cycles.
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of 24 entries
· updated 2026-09-15
| Name | Type | Description | Abilities | Weak Point | Rewards | Location |
|---|---|---|---|---|---|---|
| Gozuki | Yokai Boss | The tutorial-scale wall of Nioh 2's opening: an ox-headed demon with a club, a charge and enough health to force players to learn Burst Counters early. | Charging rush across the arena Club slam with shockwave Red burst attack countered with the Burst Counter | Horn | Soul Core | — |
| Mezuki | Yokai Boss | Gozuki's naginata-wielding counterpart, fought in the same early stretch and built to be the faster of the pair. | Lunging naginata thrust Wide sweeping combos Red burst attack | — | Soul Core | — |
| Enenra | Yokai Boss | A furnace-born smoke yokai that fights in a burning arena. | Smoke teleport Spinning whirlwind Fire projectiles and burning floor | — | Soul Core | — |
| Yatsu-no-Kami | Yokai Boss | A mass of serpents emerging from a single body, fought in a flooded cavern. | Multiple serpent head strikes Poison spit Burrowing reposition | Individual serpent heads | Soul Core | — |
| Kamaitachi | Yokai Boss | The sickle weasel fought as a highly mobile boss that rides cutting wind across the arena. | Wind dash with cutting trail Leaping sickle spins Red burst attack | — | Soul Core | — |
| Imagawa Yoshimoto | Human Boss | The first major human duel of the campaign, fought at Okehazama against the daimyo whose army the Oda are trying to survive. | Sword combos with guard cancels Parry and counterattack Ki-draining pressure strings | — | — | Okehazama |
| Saito Toshimitsu | Human Boss | A recurring swordmaster duel that turns up more than once across the campaign. | Fast iai-style draw cuts Counterattacks after blocks High-damage punish on whiffs | — | — | — |
| Magara Naotaka | Human Boss | A spear-wielding warrior boss with long reach and ice-flavoured attacks. | Long-range spear thrusts Sweeping combos Elemental weapon attacks | — | — | — |
| Kasha | Yokai Boss | The cat-wheel demon: a burning wheel with claws and a woman's face, rolling through the arena and igniting the floor. | Flaming wheel charge Claw combos Persistent fire trails | — | Soul Core | — |
| Tatarimokke | Yokai Boss | A giant owl yokai that fights from the air with sweeping dives and feathers, in an arena built around verticality. | Diving passes Feather volleys Aerial repositioning out of melee reach | — | Soul Core | — |
| Daidara Bocchi | Yokai Boss | A colossal yokai built out of the landscape itself, fought as a set-piece against a target far larger than the arena's normal enemies. | Arena-wide sweeping attacks Ground-shaking slams Multiple breakable weak points | — | Soul Core | — |
| Lady Osakabe | Yokai Boss | A noblewoman fused with a serpentine yokai form, fought in a castle interior. | Serpent strikes at range Melee claw combos Arena hazards in the castle | — | Soul Core | — |
| Shuten Doji | Yokai Boss | The legendary oni chieftain of Mount Oe, fought as one of the campaign's hardest optional-scale encounters. | Heavy club combos Feint and delayed attacks Fire and gourd-based attacks | — | Soul Core | Mount Oe |
| Yamata-no-Orochi | Yokai Boss | The eight-headed serpent of myth, staged as a multi-head encounter where each head attacks independently. | Eight independently attacking heads Elemental breath attacks Arena-wide sweeps | — | Soul Core | — |
| Otakemaru | Final Boss | The campaign's final confrontation, a multi-phase fight that pulls together everything the game teaches about Burst Counters, dark realms and yokai shift timing. | Multi-phase escalation Frequent red burst attacks Dark realm phases that drain Ki | — | Soul Core | — |
| Shibata Katsuie | Yokai Boss | An Oda retainer who has been consumed by yokai flame, fought as a mobile bruiser that never stands still long enough to be comboed comfortably. | Flame-trailing weapon combos Rushing charges across the arena Fire patches left by heavy attacks | — | Soul Core | — |
| Gyuki | Yokai Boss | A bull-bodied, spider-legged yokai that fights as a mobile siege engine. | Long straight-line charges Ranged projectile spit Ground-shaking slam | — | Soul Core | — |
| Ryomen Sukuna | Yokai Boss | A two-faced yokai that fights with a different element on each side, which is what makes the encounter hard to memorise. | Dual-element attack sets Wide sweeping melee combos Red burst attacks with short wind-ups | — | Soul Core | — |
| Kashin Koji | Human Boss | The campaign's scheming antagonist, fought as a caster rather than a swordsman. | Teleport repositioning Illusion and area attacks Summoned interference | — | — | — |
| Oda Nobunaga | Human Boss | A duel against the Oda lord himself, built around dual blades and fire. | Dual-blade pressure strings Fire-infused attacks Guard-breaking follow-ups | — | — | — |
| Maeda Toshiie | Human Boss | A spear duel against one of the Oda's senior commanders. | Long spear thrusts Stepped advancing combos Delayed follow-up strikes | — | — | — |
| Honda Tadakatsu | Human Boss | The heaviest of the human duels, fought against a warrior whose spear covers an unusually wide arc. | Wide-arc spear sweeps Heavy single-hit punishes Armoured responses to light attacks | — | — | — |
| Benkei | Human Boss | The warrior monk of the DLC chapters, fought as a giant with a polearm and a taste for overhead swings. | Overhead polearm slams Arena-wide sweeps High stagger resistance | — | — | — |
| Nightmarebringer | Final Boss | The closing fight of the DLC campaign: a colossal yokai that escalates through phases instead of changing its rules. | Multi-phase escalation Dark realm pressure Arena-wide burst attacks | — | Soul Core | — |
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